A physiologically based model of orexinergic stabilization of sleep and wake.

The orexinergic neurons of the lateral hypothalamus (Orx) are essential for regulating sleep-wake dynamics, and their loss causes narcolepsy, a disorder characterized by severe instability of sleep and wake states. However, the mechanisms through which Orx stabilize sleep and wake are not well under...

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Autores principales: Ben D Fulcher, Andrew J K Phillips, Svetlana Postnova, Peter A Robinson
Formato: article
Lenguaje:EN
Publicado: Public Library of Science (PLoS) 2014
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Acceso en línea:https://doaj.org/article/da208aeeacb54083af4217b63c70cce4
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