A physiologically based model of orexinergic stabilization of sleep and wake.
The orexinergic neurons of the lateral hypothalamus (Orx) are essential for regulating sleep-wake dynamics, and their loss causes narcolepsy, a disorder characterized by severe instability of sleep and wake states. However, the mechanisms through which Orx stabilize sleep and wake are not well under...
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Autores principales: | Ben D Fulcher, Andrew J K Phillips, Svetlana Postnova, Peter A Robinson |
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Formato: | article |
Lenguaje: | EN |
Publicado: |
Public Library of Science (PLoS)
2014
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Materias: | |
Acceso en línea: | https://doaj.org/article/da208aeeacb54083af4217b63c70cce4 |
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