DNA translocation mechanism of the MCM complex and implications for replication initiation

Eukaryotes and archaea use a heximeric ring-shaped MCM helicase to unwind the DNA template during replication. Here the authors present a crystal structure of the MCM complex from archaeon S. solfataricus bound to single-stranded DNA, and to a combination of ADP, and ATP-mimic, ADP-BeF3.

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Autores principales: Martin Meagher, Leslie B. Epling, Eric J. Enemark
Formato: article
Lenguaje:EN
Publicado: Nature Portfolio 2019
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Acceso en línea:https://doaj.org/article/da3d2f86275a48fca8e4523d176c6988
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