Knockout of the KH-Type Splicing Regulatory Protein Drives Glomerulonephritis in MRL-Fas<sup>lpr</sup> Mice

KH-type splicing regulatory protein (KSRP) is an RNA-binding protein that promotes mRNA decay and thereby negatively regulates cytokine expression at the post-transcriptional level. Systemic lupus erythematosus (SLE) is an autoimmune disease characterized by dysregulated cytokine expression causing...

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Autores principales: Lisa Schmidtke, Myriam Meineck, Sabrina Saurin, Svenja Otten, Fabian Gather, Katharina Schrick, Rudolf Käfer, Wilfried Roth, Hartmut Kleinert, Julia Weinmann-Menke, Andrea Pautz
Formato: article
Lenguaje:EN
Publicado: MDPI AG 2021
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Acceso en línea:https://doaj.org/article/da5060350d0742d68f0b00959c48e6d9
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