Knockout of the KH-Type Splicing Regulatory Protein Drives Glomerulonephritis in MRL-Fas<sup>lpr</sup> Mice

Knockout of the KH-Type Splicing Regulatory Protein Drives Glomerulonephritis in MRL-Fas<sup>lpr</sup> Mice

KH-type splicing regulatory protein (KSRP) is an RNA-binding protein that promotes mRNA decay and thereby negatively regulates cytokine expression at the post-transcriptional level. Systemic lupus erythematosus (SLE) is an autoimmune disease characterized by dysregulated cytokine expression causing...

Full description

Saved in:
Bibliographic Details
Main Authors: Lisa Schmidtke, Myriam Meineck, Sabrina Saurin, Svenja Otten, Fabian Gather, Katharina Schrick, Rudolf Käfer, Wilfried Roth, Hartmut Kleinert, Julia Weinmann-Menke, Andrea Pautz
Format: article
Language:EN
Published: MDPI AG 2021
Subjects:
systemic lupus erythematosus
glomerulonephritis
post-transcriptional regulation
cytokine
KSRP
Biology (General)
QH301-705.5
Online Access:https://doaj.org/article/da5060350d0742d68f0b00959c48e6d9
Tags: Add Tag
No Tags, Be the first to tag this record!

Internet

https://doaj.org/article/da5060350d0742d68f0b00959c48e6d9

Similar Items