Early Generation of New PrPSc on Blood Vessels after Brain Microinjection of Scrapie in Mice

ABSTRACT Aggregation of misfolded host proteins in the central nervous system is believed to be important in the pathogenic process in several neurodegenerative diseases of humans, including prion diseases, Alzheimer's disease, and Parkinson's disease. In these diseases, protein misfolding...

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Bibliographic Details
Main Authors: Bruce Chesebro, James Striebel, Alejandra Rangel, Katie Phillips, Andrew Hughson, Byron Caughey, Brent Race
Format: article
Language:EN
Published: American Society for Microbiology 2015
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Online Access:https://doaj.org/article/da548ec526a5483a8b786727f710eeb9
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