Resolution of tissue signatures of therapy response in patients with recurrent GBM treated with neoadjuvant anti-PD1

The response to neoadjuvant immune checkpoint blockade (ICB) in patients with recurrent gliolastoma multiforme (GBM) has been challenging to interpret. Here the authors develop a tumor analysis framework that reveals molecular similarities between GBM and melanoma and unique patterns of immunosuppre...

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Autores principales: Yue Lu, Alphonsus H. C. Ng, Frances E. Chow, Richard G. Everson, Beth A. Helmink, Michael T. Tetzlaff, Rohit Thakur, Jennifer A. Wargo, Timothy F. Cloughesy, Robert M. Prins, James R. Heath
Formato: article
Lenguaje:EN
Publicado: Nature Portfolio 2021
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Acceso en línea:https://doaj.org/article/da58c67153ba43c0bfe64ab0eaad9f67
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