Structural basis for the structural dynamics of human mitochondrial chaperonin mHsp60

Abstract Human mitochondrial chaperonin mHsp60 is essential for mitochondrial function by assisting folding of mitochondrial proteins. Unlike the double-ring bacterial GroEL, mHsp60 exists as a heptameric ring that is unstable and dissociates to subunits. The structural dynamics has been implicated...

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Autores principales: Joseph Che-Yen Wang, Lingling Chen
Formato: article
Lenguaje:EN
Publicado: Nature Portfolio 2021
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Acceso en línea:https://doaj.org/article/da78a54da34e4c4c96cbe02da7b7c6bd
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