Structural basis for the structural dynamics of human mitochondrial chaperonin mHsp60

Structural basis for the structural dynamics of human mitochondrial chaperonin mHsp60

Abstract Human mitochondrial chaperonin mHsp60 is essential for mitochondrial function by assisting folding of mitochondrial proteins. Unlike the double-ring bacterial GroEL, mHsp60 exists as a heptameric ring that is unstable and dissociates to subunits. The structural dynamics has been implicated...

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Autores principales: Joseph Che-Yen Wang, Lingling Chen
Formato: article
Lenguaje:EN
Publicado: Nature Portfolio 2021
Materias:
Medicine
R
Science
Q
Acceso en línea:https://doaj.org/article/da78a54da34e4c4c96cbe02da7b7c6bd
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