Structural basis for the structural dynamics of human mitochondrial chaperonin mHsp60

Abstract Human mitochondrial chaperonin mHsp60 is essential for mitochondrial function by assisting folding of mitochondrial proteins. Unlike the double-ring bacterial GroEL, mHsp60 exists as a heptameric ring that is unstable and dissociates to subunits. The structural dynamics has been implicated...

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Bibliographic Details
Main Authors: Joseph Che-Yen Wang, Lingling Chen
Format: article
Language:EN
Published: Nature Portfolio 2021
Subjects:
R
Q
Online Access:https://doaj.org/article/da78a54da34e4c4c96cbe02da7b7c6bd
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