Microglial dopamine receptor elimination defines sex-specific nucleus accumbens development and social behavior in adolescent rats

Dopaminergic circuits in the nucleus accumbens regulate reward, including social play behavior in adolescent rodents. Here, the authors show that in male but not female rats, dopamine receptors are tagged by complement for microglial phagocytosis, thus mediating changes in social behavior.

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Detalles Bibliográficos
Autores principales: Ashley M. Kopec, Caroline J. Smith, Nathan R. Ayre, Sean C. Sweat, Staci D. Bilbo
Formato: article
Lenguaje:EN
Publicado: Nature Portfolio 2018
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Acceso en línea:https://doaj.org/article/dadd63e2136e48ce8dc7b2c0ad514588
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