Replication stress induces mitotic death through parallel pathways regulated by WAPL and telomere deprotection

Replication stress induces mitotic death through parallel pathways regulated by WAPL and telomere deprotection

Mitotic catastrophe is a regulated mechanism that responds to aberrant mitoses leading to removal of damaged cells. Here the authors reveal how replication stress induces mitotic death through pathways regulated by WAPL and telomere deprotection.

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Detalles Bibliográficos
Autores principales: V. Pragathi Masamsetti, Ronnie Ren Jie Low, Ka Sin Mak, Aisling O’Connor, Chris D. Riffkin, Noa Lamm, Laure Crabbe, Jan Karlseder, David C. S. Huang, Makoto T. Hayashi, Anthony J. Cesare
Formato: article
Lenguaje:EN
Publicado: Nature Portfolio 2019
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Science
Q
Acceso en línea:https://doaj.org/article/dae63874a0924b7f84dd69ccfd135eb0
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https://doaj.org/article/dae63874a0924b7f84dd69ccfd135eb0

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