Off-the-shelf proximity biotinylation for interaction proteomics

Proximity biotinylation is a powerful tool to profile interactomes, but it requires genetic engineering of the target protein. Here, the authors develop a proximity biotinylation enzyme that can be directed to the target using antibodies, enabling interactome profiling of endogenous proteins or PTMs...

Descripción completa

Guardado en:
Detalles Bibliográficos
Autores principales: Irene Santos-Barriopedro, Guido van Mierlo, Michiel Vermeulen
Formato: article
Lenguaje:EN
Publicado: Nature Portfolio 2021
Materias:
Q
Acceso en línea:https://doaj.org/article/daee1039e77c42bc92b128ce138c9f8d
Etiquetas: Agregar Etiqueta
Sin Etiquetas, Sea el primero en etiquetar este registro!