Characteristic rotational behaviors of rod-shaped cargo revealed by automated five-dimensional single particle tracking

Distinguishing rotational motions from translational motions in the z-axis has been a long-standing challenge. Here the authors develop a five-dimensional single particle tracking method to detect rotational behaviors of nanocargos during clathrin-mediated endocytosis and intracellular transport.

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Bibliographic Details
Main Authors: Kuangcai Chen, Yan Gu, Wei Sun, Bin Dong, Gufeng Wang, Xinxin Fan, Tian Xia, Ning Fang
Format: article
Language:EN
Published: Nature Portfolio 2017
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Online Access:https://doaj.org/article/db163aa85ffc4651a3a35bd9e191d9b4
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Summary:Distinguishing rotational motions from translational motions in the z-axis has been a long-standing challenge. Here the authors develop a five-dimensional single particle tracking method to detect rotational behaviors of nanocargos during clathrin-mediated endocytosis and intracellular transport.