PURPL represses autophagic cell death to promote cutaneous melanoma by modulating ULK1 phosphorylation

Abstract Uncontrolled overactivation of autophagy may lead to autophagic cell death, suppression of which is a pro-survival strategy for tumors. However, mechanisms involving key regulators in modulating autophagic cell death remain poorly defined. Here, we report a novel long noncoding RNA, p53 upr...

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Auteurs principaux: Shuo Han, Xue Li, Ke Wang, Dingheng Zhu, Bingyao Meng, Jieyu Liu, Xiaoting Liang, Yi Jin, Xingyuan Liu, Qian Wen, Liang Zhou
Format: article
Langue:EN
Publié: Nature Publishing Group 2021
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Accès en ligne:https://doaj.org/article/db4c416fb1a0469aab12a11e92571303
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