Rebalancing of actomyosin contractility enables mammary tumor formation upon loss of E-cadherin
E-cadherin is a well-known tumor suppressor albeit loss of E-cadherin alone is insufficient to induce mammary tumorigenesis. Here the authors report that epithelial cells that have lost E-cadherin can survive by extruding to the basal lamina but require rebalancing of actomyosin contractility to dri...
Enregistré dans:
Auteurs principaux: | , , , , , , , , |
---|---|
Format: | article |
Langue: | EN |
Publié: |
Nature Portfolio
2019
|
Sujets: | |
Accès en ligne: | https://doaj.org/article/db63cd2a463f498782159daf9e40c722 |
Tags: |
Ajouter un tag
Pas de tags, Soyez le premier à ajouter un tag!
|