Computational redesign of a fluorogen activating protein with Rosetta.

The use of unnatural fluorogenic molecules widely expands the pallet of available genetically encoded fluorescent imaging tools through the design of fluorogen activating proteins (FAPs). While there is already a handful of such probes available, each of them went through laborious cycles of in vitr...

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Main Authors: Nina G Bozhanova, Joel M Harp, Brian J Bender, Alexey S Gavrikov, Dmitry A Gorbachev, Mikhail S Baranov, Christina B Mercado, Xuan Zhang, Konstantin A Lukyanov, Alexander S Mishin, Jens Meiler
Format: article
Language:EN
Published: Public Library of Science (PLoS) 2021
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Online Access:https://doaj.org/article/db709dc63ab7480d90a2d7fc01f83e8c
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