A pediatric brain tumor atlas of genes deregulated by somatic genomic rearrangement

The global impact of somatic structural variants (SSVs) on gene expression in childhood cancers is unclear. Here, the authors analyse cancer genome and RNA sequencing data of 854 pediatric brain tumours and report a landscape of genes deregulated by SSVs.

Guardado en:

Detalles Bibliográficos
Autores principales:	Yiqun Zhang, Fengju Chen, Lawrence A. Donehower, Michael E. Scheurer, Chad J. Creighton
Formato:	article
Lenguaje:	EN
Publicado:	Nature Portfolio 2021
Materias:	Science Q
Acceso en línea:	https://doaj.org/article/db8ca0e9586749df99643f4d66cc5fc9
Etiquetas:	Agregar Etiqueta Sin Etiquetas, Sea el primero en etiquetar este registro!

id	oai:doaj.org-article:db8ca0e9586749df99643f4d66cc5fc9
record_format	dspace
spelling	oai:doaj.org-article:db8ca0e9586749df99643f4d66cc5fc92021-12-02T14:26:44ZA pediatric brain tumor atlas of genes deregulated by somatic genomic rearrangement10.1038/s41467-021-21081-y2041-1723https://doaj.org/article/db8ca0e9586749df99643f4d66cc5fc92021-02-01T00:00:00Zhttps://doi.org/10.1038/s41467-021-21081-yhttps://doaj.org/toc/2041-1723The global impact of somatic structural variants (SSVs) on gene expression in childhood cancers is unclear. Here, the authors analyse cancer genome and RNA sequencing data of 854 pediatric brain tumours and report a landscape of genes deregulated by SSVs.Yiqun ZhangFengju ChenLawrence A. DonehowerMichael E. ScheurerChad J. CreightonNature PortfolioarticleScienceQENNature Communications, Vol 12, Iss 1, Pp 1-17 (2021)
institution	DOAJ
collection	DOAJ
language	EN
topic	Science Q
spellingShingle	Science Q Yiqun Zhang Fengju Chen Lawrence A. Donehower Michael E. Scheurer Chad J. Creighton A pediatric brain tumor atlas of genes deregulated by somatic genomic rearrangement
description	The global impact of somatic structural variants (SSVs) on gene expression in childhood cancers is unclear. Here, the authors analyse cancer genome and RNA sequencing data of 854 pediatric brain tumours and report a landscape of genes deregulated by SSVs.
format	article
author	Yiqun Zhang Fengju Chen Lawrence A. Donehower Michael E. Scheurer Chad J. Creighton
author_facet	Yiqun Zhang Fengju Chen Lawrence A. Donehower Michael E. Scheurer Chad J. Creighton
author_sort	Yiqun Zhang
title	A pediatric brain tumor atlas of genes deregulated by somatic genomic rearrangement
title_short	A pediatric brain tumor atlas of genes deregulated by somatic genomic rearrangement
title_full	A pediatric brain tumor atlas of genes deregulated by somatic genomic rearrangement
title_fullStr	A pediatric brain tumor atlas of genes deregulated by somatic genomic rearrangement
title_full_unstemmed	A pediatric brain tumor atlas of genes deregulated by somatic genomic rearrangement
title_sort	pediatric brain tumor atlas of genes deregulated by somatic genomic rearrangement
publisher	Nature Portfolio
publishDate	2021
url	https://doaj.org/article/db8ca0e9586749df99643f4d66cc5fc9
work_keys_str_mv	AT yiqunzhang apediatricbraintumoratlasofgenesderegulatedbysomaticgenomicrearrangement AT fengjuchen apediatricbraintumoratlasofgenesderegulatedbysomaticgenomicrearrangement AT lawrenceadonehower apediatricbraintumoratlasofgenesderegulatedbysomaticgenomicrearrangement AT michaelescheurer apediatricbraintumoratlasofgenesderegulatedbysomaticgenomicrearrangement AT chadjcreighton apediatricbraintumoratlasofgenesderegulatedbysomaticgenomicrearrangement AT yiqunzhang pediatricbraintumoratlasofgenesderegulatedbysomaticgenomicrearrangement AT fengjuchen pediatricbraintumoratlasofgenesderegulatedbysomaticgenomicrearrangement AT lawrenceadonehower pediatricbraintumoratlasofgenesderegulatedbysomaticgenomicrearrangement AT michaelescheurer pediatricbraintumoratlasofgenesderegulatedbysomaticgenomicrearrangement AT chadjcreighton pediatricbraintumoratlasofgenesderegulatedbysomaticgenomicrearrangement
_version_	1718391340517031936

A pediatric brain tumor atlas of genes deregulated by somatic genomic rearrangement

Ejemplares similares