A cysteine-based molecular code informs collagen C-propeptide assembly

Collagen proteins assemble into trimers from distinct monomers with high specificity, yet the molecular basis for this specificity remains unclear. Here the authors demonstrate the crucial role of conserved C-terminal domain cysteine residues and calcium in homotrimeric procollagen assembly.

Enregistré dans:
Détails bibliographiques
Auteurs principaux: Andrew S. DiChiara, Rasia C. Li, Patreece H. Suen, Azade S. Hosseini, Rebecca J. Taylor, Alexander F. Weickhardt, Diya Malhotra, Darrell R. McCaslin, Matthew D. Shoulders
Format: article
Langue:EN
Publié: Nature Portfolio 2018
Sujets:
Q
Accès en ligne:https://doaj.org/article/dbc3340970d64d4c9c2a223c1086ae26
Tags: Ajouter un tag
Pas de tags, Soyez le premier à ajouter un tag!