Identification of Peptide Mimotope Ligands for Natalizumab

Abstract Mimotope peptides selected from combinatorial peptide libraries can be used as capture reagents for immunoassay detection of therapeutic monoclonal antibodies (mAbs). We report the use of phage display libraries to identify peptide ligands (VeritopesTM) that bind natalizumab, a therapeutic...

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Autores principales: Laura E. Ruff, Jessica A. Pfeilsticker, Nicholas E. Johnsen, Sarah Nocchi, Bradley T. Messmer
Formato: article
Lenguaje:EN
Publicado: Nature Portfolio 2018
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Acceso en línea:https://doaj.org/article/dbcb2a18d1b547218b99e669ed8adfff
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