Inhibition of MMP2-PEX by a novel ester of dihydroxy cinnamic and linoleic acid from the seagrass Cymodocea serrulata
Abstract Matrix metalloproteinases (MMPs) are pivotal for cancer cell migration and metastasis which are generally over-expressed in such cell types. Many drugs targeting MMPs do so by binding to the conserved catalytic domains and thus exhibit poor selectivity due to domain-similarities with other...
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Main Authors: | V. S. Christina, R. Lakshmi Sundaram, V. Sivamurugan, D. Thirumal Kumar, C. D. Mohanapriya, V. L. Shailaja, S. P. Thyagarajan, C. George Priya Doss, K. Mary Elizabeth Gnanambal |
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Format: | article |
Language: | EN |
Published: |
Nature Portfolio
2021
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Subjects: | |
Online Access: | https://doaj.org/article/dbcf18e089ee464eabd1034aab9e7cd4 |
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