Development of a capture sequencing assay for enhanced detection and genotyping of tick-borne pathogens

Development of a capture sequencing assay for enhanced detection and genotyping of tick-borne pathogens

Abstract Inadequate sensitivity has been the primary limitation for implementing high-throughput sequencing for studies of tick-borne agents. Here we describe the development of TBDCapSeq, a sequencing assay that uses hybridization capture probes that cover the complete genomes of the eleven most co...

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Autores principales: Komal Jain, Teresa Tagliafierro, Adriana Marques, Santiago Sanchez-Vicente, Alper Gokden, Brian Fallon, Nischay Mishra, Thomas Briese, Vishal Kapoor, Stephen Sameroff, Cheng Guo, Luis A. Marcos, Linden Hu, W. Ian Lipkin, Rafal Tokarz
Formato: article
Lenguaje:EN
Publicado: Nature Portfolio 2021
Materias:
Medicine
R
Science
Q
Acceso en línea:https://doaj.org/article/dbd846340ea64ae88cdea56825636c91
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https://doaj.org/article/dbd846340ea64ae88cdea56825636c91

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