Impairment of mitochondria in adult mouse brain overexpressing predominantly full-length, N-terminally acetylated human α-synuclein.

While most forms of Parkinson's Disease (PD) are sporadic in nature, a small percentage of PD have genetic causes as first described for dominant, single base pair changes as well as duplication and triplication in the α-synuclein gene. The α-synuclein gene encodes a 140 amino acid residue prot...

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Autores principales: Theodore A Sarafian, Christopher M Ryan, Puneet Souda, Eliezer Masliah, Upendra K Kar, Harry V Vinters, Gary W Mathern, Kym F Faull, Julian P Whitelegge, Joseph B Watson
Formato: article
Lenguaje:EN
Publicado: Public Library of Science (PLoS) 2013
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Acceso en línea:https://doaj.org/article/dbde3621403742a398fb4f5246922592
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