An autophagy assay reveals the ESCRT-III component CHMP2A as a regulator of phagophore closure
During autophagy, phagophores elongate to form double-membrane vesicles but the mechanism behind their closure is unknown. Here, the authors develop an autophagy assay and find a role for the endosomal sorting complexes required for transport component CHMP2A as a phagophore closure regulator.
Enregistré dans:
| Auteurs principaux: | , , , , , , , , , , , , , , |
|---|---|
| Format: | article |
| Langue: | EN |
| Publié: |
Nature Portfolio
2018
|
| Sujets: | |
| Accès en ligne: | https://doaj.org/article/dc0bd3a5e9b64caca02caa285ccc24af |
| Tags: |
Ajouter un tag
Pas de tags, Soyez le premier à ajouter un tag!
|