Preliminary Assessment of the Anti-inflammatory Activity of New Structural Honokiol Analogs with a 4′-<i>O</i>-(2-Fluoroethyl) Moiety and the Potential of Their <sup>18</sup>F-Labeled Derivatives for Neuroinflammation Imaging
Neolignans honokiol and 4′-<i>O</i>-methylhonokiol (MH) and their derivatives have pronounced anti-inflammatory activity, as evidenced by numerous pharmacological studies. Literature data suggested that cyclooxygenase type 2 (COX-2) may be a target for these compounds in vitro and in viv...
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| Main Authors: | , , , , , , , , |
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| Format: | article |
| Language: | EN |
| Published: |
MDPI AG
2021
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| Subjects: | |
| Online Access: | https://doaj.org/article/dc280d6893ef40ce9b8093ad7de45e15 |
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