Optimization of methodology for the extraction of polyphenolic compounds with antioxidant potential and α-glucosidase inhibitory activity from Jamun (Syzygium cumini L.) seeds
Jamun (Syzygium cumini L.) seed is one of the rich sources of polyphenolic compounds with antioxidant potential and α-glucosidase inhibitory activity. A study was conducted to optimize the methodology for the extraction of polyphenolic compounds (total phenolic and flavonoid contents) with ant...
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| Autores principales: | , , |
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| Formato: | article |
| Lenguaje: | EN |
| Publicado: |
Society for Promotion of Horticulture - Indian Institute of Horticultural Research
2021
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| Materias: | |
| Acceso en línea: | https://doaj.org/article/dc639bb947eb4e0c9f6847dae384a2b3 |
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| Sumario: | Jamun (Syzygium cumini L.) seed is one of the rich sources of polyphenolic compounds with antioxidant potential and α-glucosidase inhibitory activity. A study was conducted to optimize the methodology for the extraction of polyphenolic compounds (total phenolic and flavonoid contents) with antioxidant potential and α-glucosidase inhibitory activity from Jamun seed powder. The study showed that the nature of solvent and extraction conditions had a significant effect on total phenolic content (TPC), total flavonoid content (TFC), antioxidant potential, and α-glucosidase inhibitory activity. The TPC varied between 6.0 (mg/g Jamun seed powder) for the acetone extract to 119.2 (mg/g) for 80% aqueous acetone extract and TFC varied between 1.06 mg/g for the acetone to 10.81 mg/g for the 80% aqueous methanol. From the study, it was apparent that an aqueous form of acetone (acetone: water 80:20, v/v) is a better solvent system for extraction of polyphenolic compounds with high antioxidant potential and α-glucosidase inhibitory activity. Ultrasonication for 60 min increased the efficiency of phenolic extraction. |
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