Analysis of Factors Influencing the Long-term Outcome in Primary Spinal Cord Tumors: Review of Literature

Introduction Primary spinal cord tumors are amenable to total surgical excision but the outcomes are still diverse. Objective The purpose of this study is to identify the significant factors which influence the long-term outcome of spinal cord tumors. Materials and Methods A to...

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Autores principales:	Uddanapalli Srinivasan, Natarajan Raghunathan
Formato:	article
Lenguaje:	EN
Publicado:	Thieme Medical Publishers, Inc. 2021
Materias:	spinal cord tumors extramedullary tumor intramedullary tumor Surgery RD1-811 Neurology. Diseases of the nervous system RC346-429
Acceso en línea:	https://doaj.org/article/dc676442df5343dcbe21f38d3ec489f0
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spelling	oai:doaj.org-article:dc676442df5343dcbe21f38d3ec489f02021-11-25T01:45:58ZAnalysis of Factors Influencing the Long-term Outcome in Primary Spinal Cord Tumors: Review of Literature2277-954X2277-916710.1055/s-0041-1726609https://doaj.org/article/dc676442df5343dcbe21f38d3ec489f02021-11-01T00:00:00Zhttp://www.thieme-connect.de/DOI/DOI?10.1055/s-0041-1726609https://doaj.org/toc/2277-954Xhttps://doaj.org/toc/2277-9167Introduction Primary spinal cord tumors are amenable to total surgical excision but the outcomes are still diverse. Objective The purpose of this study is to identify the significant factors which influence the long-term outcome of spinal cord tumors. Materials and Methods A total of 84 consecutive spinal cord tumor patients who underwent microsurgical excision during April 2003 to 2014 were retrospectively studied. Patients operated after April 2014 were not considered. Ten factors were taken and correlated with the outcome. Multiple regression analysis was used. Patients were periodically evaluated at 1, 6 months, 1, 2, and 5 years. In 72 cases, postoperative MRI scans were performed. The follow-up period ranged between 5 to 15 years. Results In our study, we had 64 extramedullary tumors and 21 intramedullary tumors with varied pathology. Axial location of the tumour (20.294/0.000), extent of the resection of the tumour (13.827/0.001), preoperative Nurick grade (11.349/0.023), and location of the tumour in the spine with respect to vertebral segments (8.151/0.017) were significant predictive factors. We had good outcomes in 65 cases and poor outcomes in 19 cases. Conclusion Our results show location of the tumor with respect to axial plane and vertebral segments were the main contributing factors. They influence the extent of excision of the spinal cord tumor. Preoperative neurological status is the fourth factor which independently determines the long-term outcome. It is one of the few papers where patients have been followed-up for a long period ranging from 5 to 15 years.Uddanapalli SrinivasanNatarajan RaghunathanThieme Medical Publishers, Inc.articlespinal cord tumorsextramedullary tumorintramedullary tumorSurgeryRD1-811Neurology. Diseases of the nervous systemRC346-429ENIndian Journal of Neurosurgery (2021)
institution	DOAJ
collection	DOAJ
language	EN
topic	spinal cord tumors extramedullary tumor intramedullary tumor Surgery RD1-811 Neurology. Diseases of the nervous system RC346-429
spellingShingle	spinal cord tumors extramedullary tumor intramedullary tumor Surgery RD1-811 Neurology. Diseases of the nervous system RC346-429 Uddanapalli Srinivasan Natarajan Raghunathan Analysis of Factors Influencing the Long-term Outcome in Primary Spinal Cord Tumors: Review of Literature
description	Introduction Primary spinal cord tumors are amenable to total surgical excision but the outcomes are still diverse. Objective The purpose of this study is to identify the significant factors which influence the long-term outcome of spinal cord tumors. Materials and Methods A total of 84 consecutive spinal cord tumor patients who underwent microsurgical excision during April 2003 to 2014 were retrospectively studied. Patients operated after April 2014 were not considered. Ten factors were taken and correlated with the outcome. Multiple regression analysis was used. Patients were periodically evaluated at 1, 6 months, 1, 2, and 5 years. In 72 cases, postoperative MRI scans were performed. The follow-up period ranged between 5 to 15 years. Results In our study, we had 64 extramedullary tumors and 21 intramedullary tumors with varied pathology. Axial location of the tumour (20.294/0.000), extent of the resection of the tumour (13.827/0.001), preoperative Nurick grade (11.349/0.023), and location of the tumour in the spine with respect to vertebral segments (8.151/0.017) were significant predictive factors. We had good outcomes in 65 cases and poor outcomes in 19 cases. Conclusion Our results show location of the tumor with respect to axial plane and vertebral segments were the main contributing factors. They influence the extent of excision of the spinal cord tumor. Preoperative neurological status is the fourth factor which independently determines the long-term outcome. It is one of the few papers where patients have been followed-up for a long period ranging from 5 to 15 years.
format	article
author	Uddanapalli Srinivasan Natarajan Raghunathan
author_facet	Uddanapalli Srinivasan Natarajan Raghunathan
author_sort	Uddanapalli Srinivasan
title	Analysis of Factors Influencing the Long-term Outcome in Primary Spinal Cord Tumors: Review of Literature
title_short	Analysis of Factors Influencing the Long-term Outcome in Primary Spinal Cord Tumors: Review of Literature
title_full	Analysis of Factors Influencing the Long-term Outcome in Primary Spinal Cord Tumors: Review of Literature
title_fullStr	Analysis of Factors Influencing the Long-term Outcome in Primary Spinal Cord Tumors: Review of Literature
title_full_unstemmed	Analysis of Factors Influencing the Long-term Outcome in Primary Spinal Cord Tumors: Review of Literature
title_sort	analysis of factors influencing the long-term outcome in primary spinal cord tumors: review of literature
publisher	Thieme Medical Publishers, Inc.
publishDate	2021
url	https://doaj.org/article/dc676442df5343dcbe21f38d3ec489f0
work_keys_str_mv	AT uddanapallisrinivasan analysisoffactorsinfluencingthelongtermoutcomeinprimaryspinalcordtumorsreviewofliterature AT natarajanraghunathan analysisoffactorsinfluencingthelongtermoutcomeinprimaryspinalcordtumorsreviewofliterature
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Analysis of Factors Influencing the Long-term Outcome in Primary Spinal Cord Tumors: Review of Literature

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