αv Integrins combine with LC3 and atg5 to regulate Toll-like receptor signalling in B cells

αv Integrins combine with LC3 and atg5 to regulate Toll-like receptor signalling in B cells

Integrins can regulate antigen-specific and innate immune receptor signalling, thereby affecting immune cell function. Here the authors show that avß3 integrin controls Toll-like receptor (TLR) signalling by regulating its trafficking to limit TLR-mediated B-cell proliferation and antibody productio...

Full description

Saved in:
Bibliographic Details
Main Authors: Mridu Acharya, Anna Sokolovska, Jenny M. Tam, Kara L. Conway, Caroline Stefani, Fiona Raso, Subhankar Mukhopadhyay, Marianela Feliu, Elahna Paul, John Savill, Richard O. Hynes, Ramnik J. Xavier, Jatin M. Vyas, Lynda M. Stuart, Adam Lacy-Hulbert
Format: article
Language:EN
Published: Nature Portfolio 2016
Subjects:
Science
Q
Online Access:https://doaj.org/article/dc8efeea8b80409f8e4a56aef9dd4da0
Tags: Add Tag
No Tags, Be the first to tag this record!

Internet

https://doaj.org/article/dc8efeea8b80409f8e4a56aef9dd4da0

Similar Items