Platelet-Mediated NET Release Amplifies Coagulopathy and Drives Lung Pathology During Severe Influenza Infection

Platelet-Mediated NET Release Amplifies Coagulopathy and Drives Lung Pathology During Severe Influenza Infection

The influenza A virus (IAV) causes a respiratory tract infection with approximately 10% of the population infected by the virus each year. Severe IAV infection is characterized by excessive inflammation and tissue pathology in the lungs. Platelet and neutrophil recruitment to the lung are involved i...

Full description

Saved in:
Bibliographic Details
Main Authors: Seok-Joo Kim, Agostina Carestia, Braedon McDonald, Amanda Z. Zucoloto, Heidi Grosjean, Rachelle P. Davis, Madison Turk, Victor Naumenko, Silvio Antoniak, Nigel Mackman, Mohamed Sarjoon Abdul-Cader, Mohamed Faizal Abdul-Careem, Morley D. Hollenberg, Craig N. Jenne
Format: article
Language:EN
Published: Frontiers Media S.A. 2021
Subjects:
influenza A virus
platelets
PAR4
thrombin
neutrophils
NETs
Immunologic diseases. Allergy
RC581-607
Online Access:https://doaj.org/article/dca945b9c1d943fb8ab37151fffb8218
Tags: Add Tag
No Tags, Be the first to tag this record!

Internet

https://doaj.org/article/dca945b9c1d943fb8ab37151fffb8218

Similar Items