Mechanisms of activation and desensitization of full-length glycine receptor in lipid nanodiscs
Glycinergic synapses play a central role in motor control and pain processing in the central nervous system. Here, authors present cryo-EM structures of the full-length glycine receptors (GlyRs) reconstituted into lipid nanodiscs in the unliganded, glycine-bound and allosteric modulator-bound confor...
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Auteurs principaux: | , , , , , , |
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Format: | article |
Langue: | EN |
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Nature Portfolio
2020
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Accès en ligne: | https://doaj.org/article/dcf52f74a2044b09b3777a173af38405 |
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