An imbalance between specialized pro-resolving lipid mediators and pro-inflammatory leukotrienes promotes instability of atherosclerotic plaques

Atherosclerosis progression is linked to inflammatory processes in the blood vessel wall. Here, the authors show that, with the progression of atherosclerosis, the resolution of inflammation is impaired as the result of an imbalance between specialized pro-resolving lipid mediators and leukotrienes.

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Auteurs principaux: Gabrielle Fredman, Jason Hellmann, Jonathan D. Proto, George Kuriakose, Romain A. Colas, Bernhard Dorweiler, E. Sander Connolly, Robert Solomon, David M. Jones, Eric J. Heyer, Matthew Spite, Ira Tabas
Format: article
Langue:EN
Publié: Nature Portfolio 2016
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Accès en ligne:https://doaj.org/article/dd0a0542340e491da02734ce00925f06
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