Promoter G-quadruplexes and transcription factors cooperate to shape the cell type-specific transcriptome

G-quadruplex (G4) structures play complex roles linked to transcription regulation. Here the authors, by comparing G4 location and transcript levels in liposarcoma and keratinocyte cells, reveal that G4s cooperate with transcription factors to determine cell-specific transcriptional programs.

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Autores principales: Sara Lago, Matteo Nadai, Filippo M. Cernilogar, Maryam Kazerani, Helena Domíniguez Moreno, Gunnar Schotta, Sara N. Richter
Formato: article
Lenguaje:EN
Publicado: Nature Portfolio 2021
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Acceso en línea:https://doaj.org/article/dd1811100f074ec8a3558e9cc0a6bb45
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