Promoter G-quadruplexes and transcription factors cooperate to shape the cell type-specific transcriptome

G-quadruplex (G4) structures play complex roles linked to transcription regulation. Here the authors, by comparing G4 location and transcript levels in liposarcoma and keratinocyte cells, reveal that G4s cooperate with transcription factors to determine cell-specific transcriptional programs.

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Bibliographic Details
Main Authors: Sara Lago, Matteo Nadai, Filippo M. Cernilogar, Maryam Kazerani, Helena Domíniguez Moreno, Gunnar Schotta, Sara N. Richter
Format: article
Language:EN
Published: Nature Portfolio 2021
Subjects:
Q
Online Access:https://doaj.org/article/dd1811100f074ec8a3558e9cc0a6bb45
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