Par-1 regulates tissue growth by influencing hippo phosphorylation status and hippo-salvador association.
The evolutionarily conserved Hippo (Hpo) signaling pathway plays a pivotal role in organ size control by balancing cell proliferation and cell death. Here, we reported the identification of Par-1 as a regulator of the Hpo signaling pathway using a gain-of-function EP screen in Drosophila melanogaste...
Enregistré dans:
Auteurs principaux: | , , , , , , , , , , , , , , , , , |
---|---|
Format: | article |
Langue: | EN |
Publié: |
Public Library of Science (PLoS)
2013
|
Sujets: | |
Accès en ligne: | https://doaj.org/article/dd46bc48791b4ce0879fd71e2a336dcc |
Tags: |
Ajouter un tag
Pas de tags, Soyez le premier à ajouter un tag!
|