Par-1 regulates tissue growth by influencing hippo phosphorylation status and hippo-salvador association.

Par-1 regulates tissue growth by influencing hippo phosphorylation status and hippo-salvador association.

The evolutionarily conserved Hippo (Hpo) signaling pathway plays a pivotal role in organ size control by balancing cell proliferation and cell death. Here, we reported the identification of Par-1 as a regulator of the Hpo signaling pathway using a gain-of-function EP screen in Drosophila melanogaste...

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Bibliographic Details
Main Authors: Hong-Ling Huang, Shimin Wang, Meng-Xin Yin, Liang Dong, Chao Wang, Wei Wu, Yi Lu, Miao Feng, Chuanyang Dai, Xiaocan Guo, Li Li, Bin Zhao, Zhaocai Zhou, Hongbin Ji, Jin Jiang, Yun Zhao, Xin-Yuan Liu, Lei Zhang
Format: article
Language:EN
Published: Public Library of Science (PLoS) 2013
Subjects:
Biology (General)
QH301-705.5
Online Access:https://doaj.org/article/dd46bc48791b4ce0879fd71e2a336dcc
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https://doaj.org/article/dd46bc48791b4ce0879fd71e2a336dcc

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