Unusual mode of dimerization of retinitis pigmentosa-associated F220C rhodopsin
Abstract Mutations in the G protein-coupled receptor (GPCR) rhodopsin are a common cause of autosomal dominant retinitis pigmentosa, a blinding disease. Rhodopsin self-associates in the membrane, and the purified monomeric apo-protein opsin dimerizes in vitro as it transitions from detergent micelle...
Enregistré dans:
| Auteurs principaux: | , , , , , , , , , , , |
|---|---|
| Format: | article |
| Langue: | EN |
| Publié: |
Nature Portfolio
2021
|
| Sujets: | |
| Accès en ligne: | https://doaj.org/article/dd6f556860b34a2ea32087d0f5c5847f |
| Tags: |
Ajouter un tag
Pas de tags, Soyez le premier à ajouter un tag!
|