Spearheading future omics analyses using dyngen, a multi-modal simulator of single cells

To benchmark single cell bioinformatics tools, data simulators can provide a robust ground truth. Here the authors present dyngen, a multi-modal simulator, and apply it to aligning cell developmental trajectories, cell-specific regulatory network inference and estimation of RNA velocity.

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Autores principales: Robrecht Cannoodt, Wouter Saelens, Louise Deconinck, Yvan Saeys
Formato: article
Lenguaje:EN
Publicado: Nature Portfolio 2021
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Acceso en línea:https://doaj.org/article/ddc181f462d749749bcb5aa8747f29b5
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