The Methionine 549 and Leucine 552 Residues of Friedelin Synthase from <i>Maytenus ilicifolia</i> Are Important for Substrate Binding Specificity
Friedelin, a pentacyclic triterpene found in the leaves of the Celastraceae species, demonstrates numerous biological activities and is a precursor of quinonemethide triterpenes, which are promising antitumoral agents. Friedelin is biosynthesized from the cyclization of 2,3-oxidosqualene, involving...
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Formato: | article |
Lenguaje: | EN |
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MDPI AG
2021
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Acceso en línea: | https://doaj.org/article/ddc35de5e5134f5c9b696820b9fe8270 |
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