NAD+ augmentation with nicotinamide riboside improves lymphoid potential of Atm −/− and old mice HSCs

Abstract NAD+ supplementation has significant benefits in compromised settings, acting largely through improved mitochondrial function and DNA repair. Elevating NAD+ to physiological levels has been shown to improve the function of some adult stem cells, with implications that these changes will lea...

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Auteurs principaux: Le Zong, Mayuri Tanaka-Yano, Bongsoo Park, Hagai Yanai, Ferda T. Turhan, Deborah L. Croteau, Jane Tian, Evandro F. Fang, Vilhelm A. Bohr, Isabel Beerman
Format: article
Langue:EN
Publié: Nature Portfolio 2021
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Accès en ligne:https://doaj.org/article/ddf050c242524dbc83af057e4f93df30
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