CLINICAL IMPORTANCE OF DETERMINATION OF HLA-DRB1 LOCUS GENES IN RHEUMATOID ARTHRITIS
Rheumatoid arthritis (RA) is a most common autoimmune inflammatory arthritis in adults. Serological marker of RA are rheumatoid factor (RF) and antibodies to cyclic citrullinated peptide (ACCP). The main genetic factor that determine predisposition to RA is HLA-DRB1 alleles. The HLA-DRB1 locus allel...
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Main Authors: | V. Guseva, S. Lapin, V. Myachikova, A. Maslyanski, A. Chuchlovin, N. Ivanova, O. Tkachenko, T. Blinova, A. Totolian |
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Format: | article |
Language: | RU |
Published: |
SPb RAACI
2019
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Subjects: | |
Online Access: | https://doaj.org/article/ddf6dedc6e0c4f90a0cfb20b76d9d2d2 |
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