Membrane cholesterol regulates TRPV4 function, cytoskeletal expression, and the cellular response to tension

Despite the association of cholesterol with debilitating pressure-related diseases such as glaucoma, heart disease, and diabetes, its role in mechanotransduction is not well understood. We investigated the relationship between mechanical strain, free membrane cholesterol, actin cytoskeleton, and the...

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Autores principales: Monika Lakk, Grace F. Hoffmann, Aruna Gorusupudi, Eric Enyong, Amy Lin, Paul S. Bernstein, Trine Toft-Bertelsen, Nanna MacAulay, Michael H. Elliott, David Križaj
Formato: article
Lenguaje:EN
Publicado: Elsevier 2021
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Acceso en línea:https://doaj.org/article/ddf84964e0c34f4f9e32ca66ec7cc420
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