Male germ cells support long-term propagation of Zika virus

Male germ cells support long-term propagation of Zika virus

Zika virus (ZIKV) can persist for months in semen and sperm. Here, the authors show that germ cells, compared to other cell types in the reproductive tract, are most susceptible to ZIKV and produce high levels of progeny virus, which coincides with decreased expression of the interferon-stimulated g...

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Auteurs principaux: Christopher L. Robinson, Angie C. N. Chong, Alison W. Ashbrook, Ginnie Jeng, Julia Jin, Haiqi Chen, Elizabeth I. Tang, Laura A. Martin, Rosa S. Kim, Reyn M. Kenyon, Eileen Do, Joseph M. Luna, Mohsan Saeed, Lori Zeltser, Harold Ralph, Vanessa L. Dudley, Marc Goldstein, Charles M. Rice, C. Yan Cheng, Marco Seandel, Shuibing Chen
Format: article
Langue:EN
Publié: Nature Portfolio 2018
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Science
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Accès en ligne:https://doaj.org/article/de04bd349fab404aa0fe17716eae5931
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https://doaj.org/article/de04bd349fab404aa0fe17716eae5931

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