Rubicon prevents autophagic degradation of GATA4 to promote Sertoli cell function.

Rubicon prevents autophagic degradation of GATA4 to promote Sertoli cell function.

Autophagy degrades unnecessary proteins or damaged organelles to maintain cellular function. Therefore, autophagy has a preventive role against various diseases including hepatic disorders, neurodegenerative diseases, and cancer. Although autophagy in germ cells or Sertoli cells is known to be requi...

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Auteurs principaux: Tadashi Yamamuro, Shuhei Nakamura, Yu Yamano, Tsutomu Endo, Kyosuke Yanagawa, Ayaka Tokumura, Takafumi Matsumura, Kiyonori Kobayashi, Hideto Mori, Yusuke Enokidani, Gota Yoshida, Hitomi Imoto, Tsuyoshi Kawabata, Maho Hamasaki, Akiko Kuma, Sohei Kuribayashi, Kentaro Takezawa, Yuki Okada, Manabu Ozawa, Shinichiro Fukuhara, Takashi Shinohara, Masahito Ikawa, Tamotsu Yoshimori
Format: article
Langue:EN
Publié: Public Library of Science (PLoS) 2021
Sujets:
Genetics
QH426-470
Accès en ligne:https://doaj.org/article/de3620c9a9d840f8b56d689a1abd0584
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Internet

https://doaj.org/article/de3620c9a9d840f8b56d689a1abd0584

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