PI3Kinase Inhibition in Hormone Receptor-Positive Breast Cancer

Derangement of the phosphatidylinositol-3 kinase (PI3K) pathway is implicated in several subtypes of breast cancers. Mutation or upregulation of PI3K enhances cancer cells’ survival, proliferation, and ability to metastasize, making it an attractive molecular target for systemic therapy. PI3K has fo...

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Bibliographic Details
Main Authors: Ajay Dhakal, Luna Acharya, Ruth O’Regan, Shipra Gandhi, Carla Falkson
Format: article
Language:EN
Published: MDPI AG 2021
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Online Access:https://doaj.org/article/de52808cef934de585708bda5de0bea6
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