Investigation of F-BAR domain PACSIN proteins uncovers membrane tubulation function in cilia assembly and transport

PACSIN proteins are known to mediate membrane tubulation. Here the authors show that PACSIN - positive membranous tubules extend from the ciliary pocket membrane and during ciliogenesis from the ciliary vesicle to the plasma membrane, called extracellular membrane channels (EMCs).

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Autores principales: Christine Insinna, Quanlong Lu, Isabella Teixeira, Adam Harned, Elizabeth M. Semler, Jim Stauffer, Valentin Magidson, Ajit Tiwari, Anne K. Kenworthy, Kedar Narayan, Christopher J. Westlake
Formato: article
Lenguaje:EN
Publicado: Nature Portfolio 2019
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Acceso en línea:https://doaj.org/article/de64a54573524588bd1cd8ede9674a09
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