Investigation of F-BAR domain PACSIN proteins uncovers membrane tubulation function in cilia assembly and transport

PACSIN proteins are known to mediate membrane tubulation. Here the authors show that PACSIN - positive membranous tubules extend from the ciliary pocket membrane and during ciliogenesis from the ciliary vesicle to the plasma membrane, called extracellular membrane channels (EMCs).

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Autores principales:	Christine Insinna, Quanlong Lu, Isabella Teixeira, Adam Harned, Elizabeth M. Semler, Jim Stauffer, Valentin Magidson, Ajit Tiwari, Anne K. Kenworthy, Kedar Narayan, Christopher J. Westlake
Formato:	article
Lenguaje:	EN
Publicado:	Nature Portfolio 2019
Materias:	Science Q
Acceso en línea:	https://doaj.org/article/de64a54573524588bd1cd8ede9674a09
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spelling	oai:doaj.org-article:de64a54573524588bd1cd8ede9674a092021-12-02T17:01:29ZInvestigation of F-BAR domain PACSIN proteins uncovers membrane tubulation function in cilia assembly and transport10.1038/s41467-018-08192-92041-1723https://doaj.org/article/de64a54573524588bd1cd8ede9674a092019-01-01T00:00:00Zhttps://doi.org/10.1038/s41467-018-08192-9https://doaj.org/toc/2041-1723PACSIN proteins are known to mediate membrane tubulation. Here the authors show that PACSIN - positive membranous tubules extend from the ciliary pocket membrane and during ciliogenesis from the ciliary vesicle to the plasma membrane, called extracellular membrane channels (EMCs).Christine InsinnaQuanlong LuIsabella TeixeiraAdam HarnedElizabeth M. SemlerJim StaufferValentin MagidsonAjit TiwariAnne K. KenworthyKedar NarayanChristopher J. WestlakeNature PortfolioarticleScienceQENNature Communications, Vol 10, Iss 1, Pp 1-17 (2019)
institution	DOAJ
collection	DOAJ
language	EN
topic	Science Q
spellingShingle	Science Q Christine Insinna Quanlong Lu Isabella Teixeira Adam Harned Elizabeth M. Semler Jim Stauffer Valentin Magidson Ajit Tiwari Anne K. Kenworthy Kedar Narayan Christopher J. Westlake Investigation of F-BAR domain PACSIN proteins uncovers membrane tubulation function in cilia assembly and transport
description	PACSIN proteins are known to mediate membrane tubulation. Here the authors show that PACSIN - positive membranous tubules extend from the ciliary pocket membrane and during ciliogenesis from the ciliary vesicle to the plasma membrane, called extracellular membrane channels (EMCs).
format	article
author	Christine Insinna Quanlong Lu Isabella Teixeira Adam Harned Elizabeth M. Semler Jim Stauffer Valentin Magidson Ajit Tiwari Anne K. Kenworthy Kedar Narayan Christopher J. Westlake
author_facet	Christine Insinna Quanlong Lu Isabella Teixeira Adam Harned Elizabeth M. Semler Jim Stauffer Valentin Magidson Ajit Tiwari Anne K. Kenworthy Kedar Narayan Christopher J. Westlake
author_sort	Christine Insinna
title	Investigation of F-BAR domain PACSIN proteins uncovers membrane tubulation function in cilia assembly and transport
title_short	Investigation of F-BAR domain PACSIN proteins uncovers membrane tubulation function in cilia assembly and transport
title_full	Investigation of F-BAR domain PACSIN proteins uncovers membrane tubulation function in cilia assembly and transport
title_fullStr	Investigation of F-BAR domain PACSIN proteins uncovers membrane tubulation function in cilia assembly and transport
title_full_unstemmed	Investigation of F-BAR domain PACSIN proteins uncovers membrane tubulation function in cilia assembly and transport
title_sort	investigation of f-bar domain pacsin proteins uncovers membrane tubulation function in cilia assembly and transport
publisher	Nature Portfolio
publishDate	2019
url	https://doaj.org/article/de64a54573524588bd1cd8ede9674a09
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Investigation of F-BAR domain PACSIN proteins uncovers membrane tubulation function in cilia assembly and transport

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