Enhanced immunocompatibility of ligand-targeted liposomes by attenuating natural IgM absorption

Targeting ligands on drug carriers can trigger immune responses. Here, the authors modify liposomes with a peptidomimetic that preserves bioactivity of the nanocarrier in blood circulation and attenuates IgM absorption, thereby improving the immunocompatibility of brain-targeted liposomes.

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Autores principales: Juan Guan, Qing Shen, Zui Zhang, Zhuxuan Jiang, Yang Yang, Meiqing Lou, Jun Qian, Weiyue Lu, Changyou Zhan
Formato: article
Lenguaje:EN
Publicado: Nature Portfolio 2018
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Acceso en línea:https://doaj.org/article/de6780060c3d401faf616e76a93f9070
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