Stiffness increases with myofibroblast content and collagen density in mesenchymal high grade serous ovarian cancer

Abstract Women diagnosed with high-grade serous ovarian cancers (HGSOC) are still likely to exhibit a bad prognosis, particularly when suffering from HGSOC of the Mesenchymal molecular subtype (50% cases). These tumors show a desmoplastic reaction with accumulation of extracellular matrix proteins a...

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Autores principales: Virginie Mieulet, Camille Garnier, Yann Kieffer, Thomas Guilbert, Fariba Nemati, Elisabetta Marangoni, Gilles Renault, Foucauld Chamming’s, Anne Vincent-Salomon, Fatima Mechta-Grigoriou
Formato: article
Lenguaje:EN
Publicado: Nature Portfolio 2021
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Acceso en línea:https://doaj.org/article/de9d7830ae0941bbbd8cf54c4242beb8
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