Stiffness increases with myofibroblast content and collagen density in mesenchymal high grade serous ovarian cancer

Stiffness increases with myofibroblast content and collagen density in mesenchymal high grade serous ovarian cancer

Abstract Women diagnosed with high-grade serous ovarian cancers (HGSOC) are still likely to exhibit a bad prognosis, particularly when suffering from HGSOC of the Mesenchymal molecular subtype (50% cases). These tumors show a desmoplastic reaction with accumulation of extracellular matrix proteins a...

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Bibliographic Details
Main Authors: Virginie Mieulet, Camille Garnier, Yann Kieffer, Thomas Guilbert, Fariba Nemati, Elisabetta Marangoni, Gilles Renault, Foucauld Chamming’s, Anne Vincent-Salomon, Fatima Mechta-Grigoriou
Format: article
Language:EN
Published: Nature Portfolio 2021
Subjects:
Medicine
R
Science
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Online Access:https://doaj.org/article/de9d7830ae0941bbbd8cf54c4242beb8
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