Stiffness increases with myofibroblast content and collagen density in mesenchymal high grade serous ovarian cancer
Abstract Women diagnosed with high-grade serous ovarian cancers (HGSOC) are still likely to exhibit a bad prognosis, particularly when suffering from HGSOC of the Mesenchymal molecular subtype (50% cases). These tumors show a desmoplastic reaction with accumulation of extracellular matrix proteins a...
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Auteurs principaux: | Virginie Mieulet, Camille Garnier, Yann Kieffer, Thomas Guilbert, Fariba Nemati, Elisabetta Marangoni, Gilles Renault, Foucauld Chamming’s, Anne Vincent-Salomon, Fatima Mechta-Grigoriou |
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Format: | article |
Langue: | EN |
Publié: |
Nature Portfolio
2021
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Accès en ligne: | https://doaj.org/article/de9d7830ae0941bbbd8cf54c4242beb8 |
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